A lot of people are waiting on more rigorous studies on larger groups of people with proper controls. Unfortunately, that takes time. Though I wouldn't rule out Orange Mad Bad either. If it turns out that HCQ works, it's a massive win for him,
Corona Virus Treatments and Vaccines - Lifesaving treatments for COVID-19 are showing positive in many cases in SK, China, EU and US.
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A lot of people are waiting on more rigorous studies on larger groups of people with proper controls. Unfortunately, that takes time. Though I wouldn't rule out Orange Mad Bad either. If it turns out that HCQ works, it's a massive win for him,
People can correct me if I’m wrong, but my understanding is that it only works well if taken in the early course of the disease, and the sick are avoiding the hospital until they’re too ill to breathe independently.
Introvertigo
kiwifarms.net
Finally proof that Hydroxychloroquine is the answer and not a vaccine.
If you've read further into the article it states that the mutation found that may pose an issue could of been an outlier, considering the other samples collected globally that did not show that variation.
Also we have some updates on the effectiveness of remisvr for inhibiting the enzyme for replication in the polymerase chain. The specific enzymes that it targets is some what demonstrated in the paper. So what I am assuming is that soon they are probably going to start with some clinical trails with remisvr, in Canada they have been pushing the Ebola drug since the beginning, before the HCL talk. Of course HCL too, but it seems like the HCL, remisver, and ivermectin. There are obviously quite a few candidates, but these seem like some of the more promising candidates. Some updates on the front runner treatments I've included in the link for some of us to see a little bit where they are at. It is frustrating to see the media spin the whole Chloroquine aspect considering that HydroxyChloroquine is a derivative of Chloroquine and is chemically different. So the whole notion of the adverse side effects are not really seen in the derivative. It also shows effectiveness because of the blood hemoglobin link that has been pointed out in COVID cases, and that is what HCL targets. Of course I am showing my bias in the HCL, but seemingly that is the most widespread being studied atm, it'll be cool to see how remisvr works too.
That study was conducted with researchers from Australia, so TBF, I wouldn't trust it as far as I could throw it. They're so ridiculously in the pocket of China here, it's painful.
Did you see that dumbass Rita Wilson and her non-sense about Chloroquine. tho?
The Remdesivir study that was done, was done in such a hasty fashion, it made Didier Raoult's HCQ trials look fancy, but the media jumped on it and ran with it.
48 hrs later...
They've halted trials in China, because they don't have enough deathly or mild patients to even trial it on.
What's so frustrating in all of this is that people keep thinking China's numbers are bullshit because "China".
"China is asshoe", no doubt, but - and those frauds who "model" things should have known this - virus outbreaks usually die out on their own. It's not a bacteria, like say, The Plague. From a historical standpoint, which is all we have, viral outbreaks behave in that fashion, time and time again. They're also modelling it on the Spanish Flu. The Spanish flu had such a high death toll because of the war. The war, malnutrition of people back home, in the trenches etc. Plus the asprin aspect, even tho debated, was most likely a huge cause.
It's patently outrageous that they fed the whole "6 Gorillion" line to everyone, the world over and it's very obvious it was not about just the virus, by the sheer over reaction everyone has indulged in.
Anyway, Macron the Cuck is taking the initiative and ordering proper trials on HCQ.
And so he should. Rauolt is one of the absolute leaders in France on this topic. He's not some two-bit quack. But it's all about political bias. Bolsonaro and Trump talked about it in a positive light, so suddenly it's an "alt right nazi drug".
Just absurd. Absurd that we've come to that point where "science" isn't about the observable, it's about who you voted for.
BTW, I suspect this trial will go the way of the Gilead ones. The virus will halt in its tracks in France and they won't get enough sick people for it. Wash, Rinse, Repeat.
Barnard
kiwifarms.net
Honestly I'm not sure if I've heard of a place that isn't trying chloroquine or hydroxychloroquine at least to some extent. They've been tested here on a small scale with good results, official trials will begin soon. It's not the miracle drug, but the Chloroquine Derangement Syndrome in the media is moronic.
In other news, Brazil claims they have a cure. For some reason this is all over Polish news but I don't see it in English-speaking media.
In other news, Brazil claims they have a cure. For some reason this is all over Polish news but I don't see it in English-speaking media.
Here's a study that shows some success with just one dose of ivermectin.
"Compared to 1,918 conventionally treated patients we observed a survival benefit for ivermectin (mortality rate 18.6% vs 7.7%). The hospital length of stay was 15.7 +/- 8.1 days vs 10.9 +/- 6.1 days, p<0.001 and intensive care unit length of stay 8.2 +/- 6.2 days vs 6.0 +/- 3.9 days, p<0.001 respectively." Note that these patients were already on mechanical ventilation. Still, shows some promise.
"Compared to 1,918 conventionally treated patients we observed a survival benefit for ivermectin (mortality rate 18.6% vs 7.7%). The hospital length of stay was 15.7 +/- 8.1 days vs 10.9 +/- 6.1 days, p<0.001 and intensive care unit length of stay 8.2 +/- 6.2 days vs 6.0 +/- 3.9 days, p<0.001 respectively." Note that these patients were already on mechanical ventilation. Still, shows some promise.
I don't understand why they've not used their medical knowledge to see that they need oxygenation and not invasive vents by now. It's insane.
That's good it's working though, just as long as people don't chug it at home I guess.
Well, how do you get more oxygen into someone's body besides just trying to pump in more after their lungs are damaged? Though I have heard of a computer model claiming that Covid could damage hemoglobin, which would also affect oxygenation. Interesting, said model also predict chloroquine would inhibit such an effect. If Covid does effect red blood cells, that would explain why anti-malarials and anti-parasite drugs are working in vitro.
We have a lot of theories out there, but not enough really rigorous data, and doctors are very reluctant to try unproven therapies on patients unless they're circling the drain and they're otherwise out of ideas. It's a much harder sell to people who are only mildly sick and are expected to recover in a week or two.
We have a lot of theories out there, but not enough really rigorous data, and doctors are very reluctant to try unproven therapies on patients unless they're circling the drain and they're otherwise out of ideas. It's a much harder sell to people who are only mildly sick and are expected to recover in a week or two.
ECMOs. Asia started using ECMOs early, in combination with other drugs and interventions, instead of just invasive vents. Some patients of course cannot be saved, no matter what you do, but ECMOs made sense for what they were being presented with.
After this is over, people need to re-evaluate why the western medical profession's experts couldn't see, from experience with the virus, that x wasn't working and they needed to do y and why their modelling was so off base.
I have family working in this field and they've all been very vocal about this one thing : The "Experts" are basically telling people to forget everything they've ever learned about medicine.
Forget that HCQ is given for Lupus, RA and Malaria. Forget that they know the side effects are minimal.
They're essentially being told to forget how to practice medicine and only listen to the experts latest drivel.
Trials are also going to present a problem.
The NYU/UofW study (headed up by Gates Foundation) on HCQ is going to probably find it "doesn't help", because they're excluding a lot of people from their trial. When you stack it in favor of an outcome, I don't know if there's a point to conducting a trial.
To experts, patients are just statistics and data. That's a massive problem. Doctors are supposed to be educated enough that they have enough trust in what they know, to be able to make the right choices. ATM they're being taught not to do that.
Sermo has been conducting studies with real doctors, gauging their opinions on what they think is working. That's a genuinely better way to get the data out in real time, in a "crisis" situation like this.
WHO: BCG vaccine for COVID-19 not recommended | NHK WORLD-JAPAN News
archived 16 Apr 2020 07:52:14 UTC
WHO says that BCG Vaccines shouldn't be used,, which means they probably SHOULD be used, since the WHO has been wrong about everything else.
ECMOs are also risky and expensive. You need a vascular surgeon to open up the carotid and the jugular to hook someone up. And even then, the argument about lack of data I made above still stands. The research required to get really good quality proof that a treatment works takes a long time, possibly years.
Doctors are also limited in what they can and can't do within the bounds of both ethical constraints and malpractice liability. The only time you can try unorthodox, risky, or unapproved methods of treatment is when someone is likely going to die soon and the standard operating procedures have all tried and failed. Morbidity and mortality inquiries always seize upon anything done to a patient that wasn't standard, and hospitals don't want to get sued/doctors don't want their licenses revoked. It sucks, but the argument is that it protects patients from doctors acting on quack ideas or using people as uninformed guinea pigs. There's a lot of information piling up about Covid. Some of it is contradictory, and a lot of it is bad science. What do you do when there's no consensus, or even worse, the waters are muddied by politics?
Doctors are also limited in what they can and can't do within the bounds of both ethical constraints and malpractice liability. The only time you can try unorthodox, risky, or unapproved methods of treatment is when someone is likely going to die soon and the standard operating procedures have all tried and failed. Morbidity and mortality inquiries always seize upon anything done to a patient that wasn't standard, and hospitals don't want to get sued/doctors don't want their licenses revoked. It sucks, but the argument is that it protects patients from doctors acting on quack ideas or using people as uninformed guinea pigs. There's a lot of information piling up about Covid. Some of it is contradictory, and a lot of it is bad science. What do you do when there's no consensus, or even worse, the waters are muddied by politics?
Do you think if Trump praises Ivermectin the media will turn against ivermectin?
The way they talk about chloroquine you'd think it's one of the most dangerous drugs known to man.
The way they talk about chloroquine you'd think it's one of the most dangerous drugs known to man.
The media would turn against water if Trump praised it.
I once saw a demo where they put a goat into a hyperbaric chamber, then proceed to replace all of it's blood with saline, and it carried on just fine. If they could mass fabricate some fiberglass cocoons to dump the sickest folks in, they could keep anyone alive, baring sepsis.
That's more for preventing someone from gushing to death as a result of trauma--and even then it's risky as hell. You need your blood inside of you if you want to fight off a disease, not this science-fiction BS.
It's for forcing oxygen. I'm not saying that you should drain their blood, only that their circulatory system doesn't even need hemablobin to keep them alive while they fight off the infection if you can get the pO2 high enough. People aren't on vents because they can't breathe in or out. They need vents to force more oxygen into their blood. So, I says, if you want to up the pressure without popping their lungs, then treat them like they've got the bends and put them in a pressure chamber.
Has anybody been keeping up with the studies of hydroxychloroquine? Have any recent studies shown effectiveness? Anecdotes?
Introvertigo
kiwifarms.net
I think there has been enough studies to know that it can work. Hence the protests to end the quarantine.
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