We all know they're going to make Ed and Gren some non-binary transxeno bullshit or something, but I'm more concerned about Faye.
Faye is probably my favorite character of the crew, and from what I can tell they're turning her from a deconstruction of the sexy fem fatal into some punk basic bitch with memory issues. Her whole character is based off of putting up a personality to make up for the lack of one she has innately, that's why she acts like such a stuck up self reliant bitch when half the time it gets her in trouble. Her whole overall arc in the show is learning she doesn't need to rely on a past she may as well forget about, everyone who knew her is dead or dying, she has no home other than the Bebop, and the people she fights with are her friends now. It takes her finding the ruins of her home for her to finally realize this.
This is probably my favorite Faye scene, especially when she bumps into Spike after recovering her memory. Spike expects some smug comeback from her back is perplexed when she just stares and apologizes. It isn't the Faye he knew, just listen to his shock when she apologizes. Post Session 24 Faye is something of a synthesis between the self reliant façade she puts up maybe as a coping mechanism and the Faye that was underneath. She is hot as hell and tough, but she is also way out of her element and has been ever since she woke up with a debt she can never pay off.
The pay off for this is in Spike's arc, in their final meeting.
Spike tells Faye how he can't run away from his past, while she tries to rebuke him explaining how there wasn't anything left for her, and there wouldn't be anything left for him either. There is some genuine tension here as though they acted antagonistically to each other over the show they have come to respect each other, maybe even have some romantic interests if you want to believe it. For Spike the past and present are inseparable due to his injury, for Faye the past and present are distinguished by a lifetime where her only childhood friend briefly calls her a ghost before remembering she was put in stasis. Faye embraces this ghost ultimately and severs a past she won't ever recover from the present.
TLDR I don't want them fucking up the hottest anime chick who smells of booze and smokes.