Science Fecal transplants led to long-term reduction in autism symptoms, study reports - The cure to autism: poop transplants

Crunchy Leaf

cronch
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Changes in social interaction and behavior are not ASD behavior that kids can grow out of, if they were then autism wouldnt be seen as such a huge issue.

Wile older autists learn how to deal with the world around them, it seems this treatment more changes the baseline for behavior. "severe" autism doesnt become "mild" with age.
There's two types of autism--with intellectual disability and without. The kind without can learn to become more normal, but the kind with will always be exceptional even if they don't have extreme behaviors, and there's nothing that can be done about that.
 

The Littlest Shitlord

True & Honest Fan
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Propionic acid produced by the gut microbes likely plays a huge part in the social impairment symptoms of autism. In fact, injections of propionic acid are actually used in rats to create an animal model of autism. As for why do autists have screwed up gut microbiota? I believe that the answer lies in a chain of consequences originating in the impaired methylation cycle seen in autism. The methylation cycle does two main things: regenerate the universal methyl donor SAM (s-adenosyl methionine), and convert the amino acid methionine to the amino acid cysteine. This pathway is the body's main source of cysteine (which is broken down in the gut rather than absorbed). Cysteine is used for a lot of important things, but the significance for the gut is that cysteine is converted to taurine which is in turn used to synthesize bile salts; furthermore, cysteine is used as a source of sulfate which also plays a role in the gut. Of course, once the gut microbiota has been screwed up by years of low cysteine, just supplementing with NAC (n-acetyl-cysteine, a form of cysteine that can be administered orally) won't fix it. Thus, fecal transplants.
 

thismanlies

The Funnest Part of Gaming is Looting Corpses.
True & Honest Fan
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Wait, so the guy who was injecting autistic kids with bleach enemas was on to something?
 
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DNA_JACKED

kiwifarms.net
There's two types of autism--with intellectual disability and without. The kind without can learn to become more normal, but the kind with will always be exceptional even if they don't have extreme behaviors, and there's nothing that can be done about that.
True, but those without still have to deal with the symptoms, mainly being unable to understand social norms unconsciously like normal people, and having to put up with the assault on the senses that modern life brings.

It would be interesting to take multiple blood tests to measure stress hormones in someone with mild, without intellectual impairment autists, then periodically take measurements while receiving these fecal transplants. If the transplants are fixing the symptoms of autism and are not simply providing a bonus to coping mechanisms, then logically the levels of stress hormones these individuals would have in highly stressful (to them) situations would be dramatically decreasing.

That would be incredibly difficult to measure accurately, but if it was possible and it did show a remarked improvement, then this would be a legitimate "autism treatment" as opposed to merely masking the symptoms and enhancing coping methods. if true, that would be huge news, especially as it is looking more and more like the gut microbe has an incredible effect on our mental state.
 
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Foxxo

OH LAWD HE COMING
kiwifarms.net
Propionic acid produced by the gut microbes likely plays a huge part in the social impairment symptoms of autism. In fact, injections of propionic acid are actually used in rats to create an animal model of autism. As for why do autists have screwed up gut microbiota? I believe that the answer lies in a chain of consequences originating in the impaired methylation cycle seen in autism. The methylation cycle does two main things: regenerate the universal methyl donor SAM (s-adenosyl methionine), and convert the amino acid methionine to the amino acid cysteine. This pathway is the body's main source of cysteine (which is broken down in the gut rather than absorbed). Cysteine is used for a lot of important things, but the significance for the gut is that cysteine is converted to taurine which is in turn used to synthesize bile salts; furthermore, cysteine is used as a source of sulfate which also plays a role in the gut. Of course, once the gut microbiota has been screwed up by years of low cysteine, just supplementing with NAC (n-acetyl-cysteine, a form of cysteine that can be administered orally) won't fix it. Thus, fecal transplants.
So you're saying that autism's symptoms aren't entirely genetic? You better keep this under wraps before the anti-vaxxers find out.
 

Dunkirk

My other car is a STUG
kiwifarms.net
Wait, so the guy who was injecting autistic kids with bleach enemas was on to something?
No, if anything he was doing the exact opposite of what this would do. Instead of donating new fecal bacteria to help balance things out or just outright introduce missing kinds, a bleach enema would absolutely destroy the unbalanced fecal bacteria in somebody's gut. From my basic medical knowledge the comparison is like a vaccine teaching white blood cells how to balance itself to fight something, VS. Aids which would just cause them to kill themselves.

It's entirely possible that if this is true, his bleach enemas might have made people more autistic than when they had their asshole intact.
 

Kalishnakov

kiwifarms.net



As funny as 'poop transplants' sound, I thought it would be interesting to supplement this article with this for a better understanding of fecal transplants.
Not about "poop" transplants, but related to the microflora/ fauna that the children are not inoculated with at birth. Many kids born via Cesarean section were found to have higher rates of Autism. Which may or may not be causally linked to the presence or lack thereof of specific bacteria that are present in the vaginal canal. The "poop" is the location for the anaerobic bacteria which give off their own 'shit' which apparently crosses the blood brain barrier affecting behavior.
 

Banh Xeo

Người chiến thắng, người chiến thắng, bữa tối gà
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I applaud this man and his lifetime achievement of getting autistic kids to swap poops and put them in their butts.
And they called it science.
Next up, seeing if you really can talk autistics out of their clothes by telling them ghost stories.
 
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